Description

4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine, 5,6-Dihydro-9-Methoxy-1-(4-Methoxyphenyl)-4-Methyl- is a high-purity, complex heterocyclic compound belonging to the benzodiazepine class, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate fused triazolo-benzodiazepine structure makes it a valuable scaffold for synthesizing novel active pharmaceutical ingredients (APIs) targeting the central nervous system. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel benzodiazepine-derived drug candidates.
• Neurological Research: Used in the development of compounds for studying GABAA receptor modulation and related neurological pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage drug development services.

Basic Information

Product Name	4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine, 5,6-Dihydro-9-Methoxy-1-(4-Methoxyphenyl)-4-Methyl-
CAS No.	942928-21-4
Molecular Formula	C19H18N4O2
Molecular Weight	334.37 g/mol
Synonyms	5,6-Dihydro-9-methoxy-1-(4-methoxyphenyl)-4-methyl-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; 4-Methyl-9-methoxy-1-(4-methoxyphenyl)-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine; Triazolobenzodiazepine Derivative 942928-21-4; CAS 942928-21-4
EINECS	Contact for details

Quality Control

Our 4H-[1,2,4]Triazolo[4,3-A][1,5]Benzodiazepine intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.