Description

5-Ethyl-5-Isobutylbarbituric Acid is a key barbiturate derivative primarily utilized as a critical pharmaceutical intermediate. Its significance lies in its role as a precursor in the synthesis of various sedative-hypnotic agents and other specialized organic compounds. This high-purity chemical is essential for manufacturers and research institutions in the pharmaceutical, fine chemical, and life science sectors requiring reliable building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of barbiturate-based active pharmaceutical ingredients (APIs) and other therapeutic agents.
• Chemical Synthesis: Serves as a versatile precursor in organic synthesis for creating novel compounds in research and development.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Employed in life science research to study neurological pathways and receptor interactions.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high-purity barbiturate structures.

Basic Information

Product Name	5-Ethyl-5-Isobutylbarbituric Acid
CAS No.	1135-61-1
Molecular Formula	C10H16N2O3
Molecular Weight	212.25 g/mol
Synonyms	5-Ethyl-5-(2-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-isobutylbarbituric acid; Ethylisobutylbarbituric Acid; NSC 406042; Butalbital Impurity; AI3-03128; 5-Ethyl-5-isobutyl-1H,3H,5H-pyrimidine-2,4,6-trione
EINECS	214-500-9

Quality Control

Our 5-Ethyl-5-Isobutylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.