Description

Doxefazepam is a benzodiazepine derivative with specific pharmacological activity. This compound is a key intermediate in advanced pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of proprietary benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and clinical research for studying structure-activity relationships (SAR) within the benzodiazepine class.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Chemical Synthesis: Acts as a precursor for the development of new chemical entities (NCEs) with potential anxiolytic or sedative properties.

Basic Information

Product Name	Doxefazepam
CAS No.	40762-15-0
Molecular Formula	C16H12ClFN2O3
Molecular Weight	334.73 g/mol
Synonyms	7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one; Doxefazepamum; 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-; (3S)-7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2H-1,4-benzodiazepin-2-one; S-4507; S4507
EINECS	Contact for details

Quality Control

Our Doxefazepam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other chromatographic techniques, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.