Description

1-Cyclohexyl-5-Isopropyl-3-Phenylbarbituric Acid is a specialized barbiturate derivative with a unique sterically hindered molecular structure. This compound is valued as a critical pharmaceutical intermediate and a versatile research chemical for developing novel therapeutic agents. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical and fine chemical sectors for synthesis and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targeted drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and screening new barbiturate analogs with potential sedative, hypnotic, or anticonvulsant properties.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development, validation, and quality control testing.
• Academic & Industrial R&D: Employed in studies investigating structure-activity relationships (SAR) and metabolic pathways of barbiturates.
• Process Chemistry: Utilized in route scouting and optimization for the commercial-scale manufacturing of complex organic molecules.

Basic Information

Product Name	1-Cyclohexyl-5-Isopropyl-3-Phenylbarbituric Acid
CAS No.	1045-95-0
Molecular Formula	C19H24N2O3
Molecular Weight	328.41 g/mol
Synonyms	5-Isopropyl-1-cyclohexyl-3-phenylbarbituric Acid; 3-Phenyl-1-cyclohexyl-5-isopropylbarbituric Acid; 1-Cyclohexyl-5-(1-methylethyl)-3-phenyl-2,4,6(1H,3H,5H)-pyrimidinetrione; NSC 172755; 5-Isopropyl-3-phenyl-1-cyclohexylbarbituric Acid
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-5-Isopropyl-3-Phenylbarbituric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.