Description

2-(4-Methylpiperazin-1-Yl)Pyrimidine-5-Boronic Acid Pinacol Ester is a high-value, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research.
• Agrochemical Development: Used to create complex heterocyclic structures found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and protein interactions.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.
• Process Chemistry: Used in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	2-(4-Methylpiperazin-1-Yl)Pyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	942922-07-8
Molecular Formula	C15H25BN4O2
Molecular Weight	304.20 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(4-methylpiperazin-1-yl)pyrimidine; 2-(4-Methyl-1-piperazinyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-(4-Methylpiperazin-1-yl)pyrimidine-5-boronic acid pinacol ester; 5-Borono-2-(4-methyl-1-piperazinyl)pyrimidine, pinacol ester; 2-(N-Methylpiperazino)pyrimidine-5-boronic acid pinacol ester; B-[2-(4-Methyl-1-piperazinyl)-5-pyrimidinyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Methylpiperazin-1-Yl)Pyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.