Description

Sodium(5S)-3-Acetyl-5-[(S)-1-Methylpropyl]-4-Hydroxy-3-Pyrroline-2-Olate is a high-purity, chiral pyrroline derivative salt with significant utility in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of complex pharmaceutical molecules and fine chemicals. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries where precise stereochemistry is paramount for biological activity and product efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic disorders.
• Asymmetric Synthesis: Used as a ligand or catalyst precursor in enantioselective reactions to produce optically pure compounds.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require specific chiral configurations.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Item	Details
Product Name	Sodium(5S)-3-Acetyl-5-[(S)-1-Methylpropyl]-4-Hydroxy-3-Pyrroline-2-Olate
CAS No.	1013-59-8
Molecular Formula	C10H16NNaO3
Molecular Weight	221.23 g/mol
Synonyms	Sodium 3-Acetyl-5-[(1S)-1-methylpropyl]-4-hydroxy-1H-pyrrole-2-carboxylate; (5S)-3-Acetyl-5-[(1S)-1-Methylpropyl]-4-Hydroxy-3-Pyrroline-2-Olic Acid Sodium Salt; Sodium 3-Acetyl-5-sec-butyl-4-hydroxypyrrole-2-carboxylate; 2-Pyrrolinecarboxylic acid, 3-acetyl-5-[(1S)-1-methylpropyl]-4-hydroxy-, sodium salt, (5S)-; L-ACBC derivative sodium salt
EINECS	Contact for details

Quality Control

Our Sodium(5S)-3-Acetyl-5-[(S)-1-Methylpropyl]-4-Hydroxy-3-Pyrroline-2-Olate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent moisture uptake and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.