Description

Lithium, [4-(2-Methyl-1,3-Dioxan-2-Yl)Phenyl]- (9Ci) is a specialized organolithium compound, a key building block in advanced organic synthesis. This compound matters for its role as a highly reactive nucleophile and base, enabling the formation of critical carbon-carbon bonds under controlled conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the phenyl-lithium moiety into complex molecules.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for generating specialized ligands and organometallic catalysts used in asymmetric synthesis and polymerization.
• Materials Science Research: Employed in the development of novel organic electronic materials, including charge-transport layers and light-emitting compounds.
• Fine Chemical Manufacturing: Applied in the multi-step synthesis of high-value, complex fine chemicals and flavors/fragrances.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new reaction pathways in organic chemistry laboratories.

Basic Information

Product Name	Lithium, [4-(2-Methyl-1,3-Dioxan-2-Yl)Phenyl]- (9Ci)
CAS No.	110347-00-7
Molecular Formula	C11H13LiO2
Molecular Weight	184.16 g/mol
Synonyms	4-(2-Methyl-1,3-dioxan-2-yl)phenyllithium; [4-(2-Methyl-1,3-dioxan-2-yl)phenyl]lithium; 2-(4-Lithiophenyl)-2-methyl-1,3-dioxane; p-(2-Methyl-1,3-dioxan-2-yl)phenyllithium; Lithium (4-(2-methyl-1,3-dioxan-2-yl)phenyl); 110347-00-7 (CAS); Lithiated 4-(2-Methyl-1,3-dioxan-2-yl)benzene
EINECS	Contact for details

Quality Control

Our Lithium, [4-(2-Methyl-1,3-Dioxan-2-Yl)Phenyl]- (9Ci) is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed to confirm identity, purity, and solution concentration (typically supplied in an appropriate organic solvent such as THF or diethyl ether). Certificates of Analysis (COA) detailing assay, impurity profile, and solvent content are provided. We adhere to cGMP principles where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and reactivity as a strong alkali/organic solvent, this material must be stored under a dry, inert gas atmosphere (argon or nitrogen) at temperatures recommended for the specific solvent formulation, typically between 2°C and 8°C for extended stability. The container must be kept in a cool, dry, well-ventilated area away from moisture, heat, and incompatible materials.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to slightly yellow
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 0.5 M in specified solvent (Typical: 0.5-1.0 M)
Purity (NMR)	≥ 95% (relative)
Solvent	As specified (e.g., THF, Diethyl ether)
Residual Base (as LiOH)	Reported on COA
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.