Description

Sodium 2-Methylpropanolate is the sodium salt of 2-methylpropanol (isobutanol). This compound serves as a powerful, non-nucleophilic base and a versatile reagent in organic synthesis, valued for its ability to deprotonate weakly acidic substrates and initiate polymerization reactions. It is a critical intermediate for manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop advanced materials and active ingredients.

Application

• Pharmaceutical Synthesis: Employed as a key base in the production of active pharmaceutical ingredients (APIs), particularly for deprotonation steps and the generation of carbanions.
• Polymerization Catalyst/Initiator: Used as an anionic initiator for the polymerization of monomers like styrene, butadiene, and methacrylates to produce synthetic rubbers and high-performance plastics.
• Agrochemical Intermediate: Acts as a building block in the synthesis of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Reagent: Facilitates condensation reactions, esterifications, and the preparation of other metal alkoxides in fine chemical production.
• Cross-Coupling Reactions: Utilized as a base in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for constructing complex organic molecules.
• Chemical Research & Development: Serves as a fundamental reagent in R&D laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	Sodium 2-Methylpropanolate
CAS No.	13259-29-5
Molecular Formula	C4H9NaO
Molecular Weight	96.10 g/mol
Synonyms	Sodium Isobutoxide; Sodium tert-Butoxide (common misnomer); Isobutanol, sodium salt; Sodium isobutanolate; 2-Methyl-1-propanol, sodium salt; Sodium salt of isobutyl alcohol; NaOiBu
EINECS	Contact for details

Quality Control

Our Sodium 2-Methylpropanolate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets precise specifications for purity and reactivity. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with every shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or lumps
Identification (IR)	Conforms
Assay (Titration)	≥ 95.0%
Solubility (in Toluene/THF)	Clear solution
Residual Solvent (GC)	Contact for details
Heavy Metals (as Pb)	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.