Description

Benzaldehyde, 4-[1-(Phenylsulfonyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]- is a sophisticated high-purity organic intermediate featuring both a benzaldehyde moiety and a protected boronic ester (pinacol boronate) group. This compound is critically important for Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing fused pyrrolopyridine scaffolds.
• Suzuki-Miyaura Cross-Coupling: The pinacol boronate ester group enables efficient palladium-catalyzed carbon-carbon bond formation with aryl/heteroaryl halides.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a precursor for creating labeled molecules or probes used to study biological pathways.
• Advanced Material Synthesis: Potential intermediate in the development of organic electronic materials or ligands for catalysts.

Basic Information

Item	Details
Product Name	Benzaldehyde, 4-[1-(Phenylsulfonyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]-
CAS No.	942921-70-2
Molecular Formula	C28H27BN2O5S
Molecular Weight	514.40 g/mol
Synonyms	4-[1-(Phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl]benzaldehyde; 2-(4-Formylphenyl)-1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-2-(4-formylphenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolo[2,3-b]pyridine; Boronic acid, B-[1-(phenylsulfonyl)-2-(4-formylphenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our Benzaldehyde, 4-[1-(Phenylsulfonyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive cross-coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.