Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-6-Chloro- is a high-purity halogenated heterocyclic building block of significant importance in advanced organic synthesis. This compound is specifically engineered to serve as a critical intermediate in the development of novel, complex molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs, particularly for the synthesis of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Kinase Inhibitor Development: The pyrrolopyridine core is a privileged scaffold in the design of potent and selective kinase inhibitors.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides.
• Material Science Research: Utilized in the creation of novel organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-6-Chloro-
CAS No.	942920-50-5
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	4-Bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-4-bromo-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-6-chloro-7-azaindole; 6-Chloro-4-bromo-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-bromo-6-chloro-; 7-Azaindole, 4-bromo-6-chloro-; 4-Bromo-6-chloro-1H-7-azaindole
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-6-Chloro- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.