Description

Benzenemethanamine, N,n-Dimethyl-4-[1-(Phenylsulfonyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]- is a sophisticated, multi-functional organic compound featuring a boronic ester pinacol group and a pyrrolopyridine core, making it a valuable advanced intermediate in modern synthetic chemistry. Its primary commercial value lies in its role as a key building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity chemical is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for Suzuki-Miyaura cross-coupling reactions and other critical synthetic transformations.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester moiety makes it an excellent partner for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds, a fundamental step in constructing complex organic molecules.
• Agrochemical Research: Used in the discovery and development of novel herbicides, fungicides, and insecticides that require complex heterocyclic structures.
• Material Science Precursor: Employed in the research of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where its conjugated system is advantageous.
• Chemical Biology Probe Development: Utilized in creating molecular probes and labeled compounds for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Provides a reliable, well-defined intermediate for optimizing synthetic routes from laboratory scale to pilot plant and commercial production.

Basic Information

Item	Detail
Product Name	Benzenemethanamine, N,n-Dimethyl-4-[1-(Phenylsulfonyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]-
CAS No.	942919-72-4
Molecular Formula	C30H34BN3O4S
Molecular Weight	543.49 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-[4-(dimethylamino)benzyl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Benzenesulfonyl)-2-[4-(dimethylamino)benzyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; N,N-Dimethyl-4-[1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl]benzenemethanamine; Boronic ester pyrrolopyridine intermediate; Sulfonated pyrrolopyridine boronate
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanamine, N,n-Dimethyl-4-[1-(Phenylsulfonyl)-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrrolo[2,3-B]Pyridin-2-Yl]- is produced and analyzed under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles from advanced analytical techniques (HPLC, NMR, LC-MS) are available upon request. We support our partners with the documentation required for regulatory filings and supply chain audits.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Recommended storage temperature is 2-8°C for prolonged periods; allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.