Description

Methyl 3-Chloro-4-Cyclopropyl-2,4-Dioxobutanoate is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclopropyl and dioxobutanoate functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in the development and production of new generation pesticides and herbicides due to its reactive chloro and keto ester functionalities.
• Organic Synthesis: Serves as a versatile precursor for constructing cyclopropane-containing compounds and other complex heterocycles in academic and industrial R&D.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity, structurally defined intermediates.

Basic Information

Product Name	Methyl 3-Chloro-4-Cyclopropyl-2,4-Dioxobutanoate
CAS No.	942852-90-6
Molecular Formula	C8H9ClO4
Molecular Weight	204.61 g/mol
Synonyms	Methyl 3-chloro-4-cyclopropyl-2,4-dioxobutanoate; 3-Chloro-4-cyclopropyl-2,4-dioxobutanoic acid methyl ester; 942852-90-6; Methyl 3-chloro-4-cyclopropyl-2,4-dioxobutyrate; Butanoic acid, 3-chloro-4-cyclopropyl-2,4-dioxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-4-Cyclopropyl-2,4-Dioxobutanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthesis applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.