Description

2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]-6-benzoxazolamine is a high-value, functionalized benzoxazole derivative containing a pinacol boronate ester group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting CNS disorders, oncology, and inflammation.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient and selective formation of biaryl and heterobiaryl structures essential for medicinal chemistry and material science.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in display and lighting technologies.
• Ligand Synthesis: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Incorporated into specialty polymers to impart specific optical, electronic, or mechanical properties.

Basic Information

Product Name	2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]-6-benzoxazolamine
CAS No.	942589-97-1
Molecular Formula	C19H21BN2O3
Molecular Weight	336.19 g/mol
Synonyms	6-Amino-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]benzoxazole; 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3-benzoxazol-6-amine; 6-Benzoxazolamine, 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; Pinacol [4-(6-Aminobenzoxazol-2-yl)phenyl]boronate; 2-(4-Bpin)phenyl-6-aminobenzoxazole
EINECS	Contact for details

Quality Control

Our production of this high-purity boronic ester adheres to stringent quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.