Description

6-Chloro-5-Methyl-Nicotinic Acid Ethyl Ester is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Used in the research and preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for advanced materials.
• Custom Synthesis and Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to specific client requirements.

Basic Information

Product Name	6-Chloro-5-Methyl-Nicotinic Acid Ethyl Ester
CAS No.	942511-70-8
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	Ethyl 6-Chloro-5-methylnicotinate; 6-Chloro-5-methyl-3-pyridinecarboxylic acid ethyl ester; 5-Methyl-6-chloronicotinic acid ethyl ester; 3-Carbethoxy-6-chloro-5-methylpyridine; 6-Chloro-5-methyl-pyridine-3-carboxylic acid ethyl ester; Ethyl 6-chloro-5-methyl-3-pyridinecarboxylate; 942511-70-8
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Methyl-Nicotinic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.