Description

Ethanone, 2,2,2-Trifluoro-1-(1,2,3,4-Tetrahydronaphthalen-1,4-Imin-9-Yl)- is a specialized trifluoromethyl ketone derivative that serves as a high-value synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring a fused tetrahydronaphthalene ring system and a reactive imine-ketone motif, makes it a critical building block for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and for introducing the pharmacologically beneficial trifluoromethyl group into lead compounds.
• Organic Synthesis Building Block: Employed in advanced organic reactions, including cyclizations and cross-couplings, to create complex heterocyclic and polycyclic structures.
• Material Science Research: Potential intermediate for synthesizing specialty chemicals and functional materials with unique electronic or optical properties.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(1,2,3,4-Tetrahydronaphthalen-1,4-Imin-9-Yl)-
CAS No.	942491-77-2
Molecular Formula	C₁₃H₁₀F₃NO
Molecular Weight	253.22 g/mol
Synonyms	2,2,2-Trifluoro-1-(1,2,3,4-tetrahydronaphthalen-1,4-imin-9-yl)ethanone; 1,2,3,4-Tetrahydro-9-(2,2,2-trifluoroacetyl)-1,4-iminonaphthalene; 9-(2,2,2-Trifluoroacetyl)-1,2,3,4-tetrahydro-1,4-iminonaphthalene; Trifluoroacetyl-tetrahydro-iminonaphthalene; TFATIN; CAS 942491-77-2
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(1,2,3,4-Tetrahydronaphthalen-1,4-Imin-9-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable consistency and traceability for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.