Description

4-(3-Bromo-Phenyl)-3-Oxo-Butyric Acid Methyl Ester is a high-purity, versatile organic building block and key synthetic intermediate. This compound is valued for its reactive β-keto ester functionality and bromoaryl substituent, enabling its use in complex multi-step synthesis. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing substituted phenyl and β-keto ester motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic ring for further functionalization.
• Organic Synthesis Building Block: Employed in various name reactions such as Michael additions, Claisen condensations, and cyclization reactions to form heterocyclic compounds.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and process chemistry optimization in both academic and industrial laboratories.

Basic Information

Product Name	4-(3-Bromo-Phenyl)-3-Oxo-Butyric Acid Methyl Ester
CAS No.	942474-94-4
Molecular Formula	C11H11BrO3
Molecular Weight	271.11 g/mol
Synonyms	Methyl 4-(3-bromophenyl)-3-oxobutanoate; 3-Oxo-4-(3-bromophenyl)butyric acid methyl ester; Methyl 3-oxo-4-(m-bromophenyl)butyrate; 4-(3-Bromophenyl)-3-oxobutyric acid methyl ester; 3-Bromo-β-keto ester intermediate; Butyric acid, 4-(3-bromophenyl)-3-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(3-Bromo-Phenyl)-3-Oxo-Butyric Acid Methyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.