Description

1-(4-Amino-2-Nitrophenyl)Piperidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct aromatic nitro and amino functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical producers engaged in creating new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex piperidine-containing molecular scaffolds.
• Research & Development: Essential for medicinal chemistry programs in academic and industrial settings for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production scale-up of specific APIs requiring this precise chemical moiety.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized azo dyes and pigments due to its aromatic amine and nitro groups.

Basic Information

Product Name	1-(4-Amino-2-Nitrophenyl)Piperidine-4-Carboxamide
CAS No.	942474-90-0
Molecular Formula	C12H16N4O3
Molecular Weight	264.28 g/mol
Synonyms	4-Amino-2-nitro-N-(piperidin-4-yl)benzamide; Piperidine-4-carboxamide, 1-(4-amino-2-nitrophenyl)-; 1-(4-Amino-2-nitrophenyl)-4-piperidinecarboxamide; 942474-90-0; 4-Amino-2-nitrobenzoic acid piperidin-4-ylamide; 1-(4-Amino-2-nitrophenyl)piperidine-4-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-2-Nitrophenyl)Piperidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.