Description

1-[2-Chloro-4-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides, leveraging its specific chlorinated and sulfonyl-substituted phenylpiperidine structure.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scaled-up synthesis of proprietary APIs requiring this specific carboxamide moiety.
• Biochemical Tool Compound: Utilized in life science research as a probe or inhibitor to study specific biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom chemical synthesis services catering to the fine chemical and pharmaceutical industries.

Basic Information

Product Name	1-[2-Chloro-4-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxamide
CAS No.	942474-89-7
Molecular Formula	C14H17ClN2O3S
Molecular Weight	328.81 g/mol
Synonyms	1-(2-Chloro-4-methanesulfonylphenyl)piperidine-3-carboxamide; 1-[2-Chloro-4-(methylsulfonyl)phenyl]-3-piperidinecarboxamide; 3-Carbamoyl-1-[2-chloro-4-(methylsulfonyl)phenyl]piperidine; Piperidine-3-carboxamide, 1-[2-chloro-4-(methylsulfonyl)phenyl]-; 942474-89-7; UNII-9B8I7D8G7F; 9B8I7D8G7F; 1-(2-Chloro-4-(methylsulfonyl)phenyl)piperidine-3-carboxylic acid amide
EINECS	Contact for details

Quality Control

Our 1-[2-Chloro-4-(Methylsulfonyl)Phenyl]Piperidine-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are available upon request, and we can support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.