Description

1-(4-Fluoro-2-Nitrophenyl)-3-Methylpiperidine is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine and fluorinated nitrophenyl structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and receptor-targeting drugs. It is an essential building block for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in novel drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel therapeutic agents, especially those targeting neurological pathways.
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its modifiable functional groups.
• Chemical Research: Serves as a versatile scaffold in academic and industrial research for exploring new chemical entities and reaction methodologies.
• Agrochemical Synthesis: Potential intermediate in the development of advanced crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of specialty chemicals and functional materials requiring specific aromatic and heterocyclic components.

Basic Information

Product Name	1-(4-Fluoro-2-Nitrophenyl)-3-Methylpiperidine
CAS No.	942474-32-0
Molecular Formula	C12H15FN2O2
Molecular Weight	238.26 g/mol
Synonyms	3-Methyl-1-(4-fluoro-2-nitrophenyl)piperidine; 1-(4-Fluoro-2-nitrophenyl)-3-methylpiperidine; 942474-32-0; 3-Methyl-1-(4-fluoro-2-nitro-phenyl)piperidine; 4-Fluoro-2-nitro-1-(3-methylpiperidin-1-yl)benzene; 1-(4-Fluoro-2-nitrophenyl)-3-methyl-piperidine; 1-(4-Fluoro-2-nitrophenyl)-3-methylpiperidine (CAS 942474-32-0)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-2-Nitrophenyl)-3-Methylpiperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider storing under an inert gas such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.