Description

2,5-Dibromoisonicotinic Acid is a halogenated derivative of isonicotinic acid, serving as a versatile and high-value brominated building block in advanced organic synthesis. This compound matters for its role in introducing bromine atoms at specific positions on the pyridine ring, enabling precise structural modifications for the development of novel molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating active ingredients, intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the bromine atoms facilitate further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or organic semiconductors.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig amination for constructing complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2,5-Dibromoisonicotinic Acid
CAS No.	942473-59-8
Molecular Formula	C6H3Br2NO2
Molecular Weight	280.90 g/mol
Synonyms	2,5-Dibromopyridine-4-carboxylic Acid; 4-Pyridinecarboxylic Acid, 2,5-Dibromo-; Isonicotinic Acid, 2,5-Dibromo-; 2,5-Dibromo-4-pyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2,5-Dibromoisonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.