Description

Methyl 5-Chloro-2-Ethynylbenzoate is a high-purity, specialized organic building block featuring a benzoate ester core substituted with both chloro and ethynyl functional groups. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists exploring new polymers and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in creating molecular probes and tags for studying biological processes via click chemistry reactions.
• Organic Synthesis: A versatile synthon for constructing complex aromatic and heterocyclic compounds in academic and industrial laboratories.

Basic Information

Product Name	Methyl 5-Chloro-2-Ethynylbenzoate
CAS No.	942273-26-9
Molecular Formula	C10H7ClO2
Molecular Weight	194.61 g/mol
Synonyms	5-Chloro-2-ethynylbenzoic acid methyl ester; Methyl 5-chloro-2-ethynylbenzoate; Benzoic acid, 5-chloro-2-ethynyl-, methyl ester; 2-Ethynyl-5-chlorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Chloro-2-Ethynylbenzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.