Description

2-(tert-Butyloxycarbonyl-Methylamino)-5-Iodo-3-Methylpyridine CAS NO 942206-08-8 is a high-purity, functionalized pyridine derivative designed for advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate, enabling the construction of complex molecules through its reactive iodine and protected amine functionalities. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides requiring specific heterocyclic scaffolds.
• Ligand Precursor: Can be utilized to synthesize complex nitrogen-containing ligands for catalysis.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes for biochemical research.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.

Basic Information

Product Name	2-(tert-Butyloxycarbonyl-Methylamino)-5-Iodo-3-Methylpyridine
CAS No.	942206-08-8
Molecular Formula	C12H17IN2O2
Molecular Weight	348.18 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)(methyl)amino]-5-iodo-3-methylpyridine; 5-Iodo-3-methyl-2-[(methyl)(tert-butoxycarbonyl)amino]pyridine; Boc-N(Me)-2-amino-5-iodo-3-methylpyridine; 2-(N-Boc-N-methylamino)-5-iodo-3-methylpyridine; 2-(N-Methyl-N-Boc-amino)-5-iodo-3-methylpyridine; tert-Butyl methyl(5-iodo-3-methylpyridin-2-yl)carbamate; 942206-08-8
EINECS	Contact for details

Quality Control

Every batch of 2-(tert-Butyloxycarbonyl-Methylamino)-5-Iodo-3-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.