Description

5-Bromo-2'-Chloro-[3,4']-Bipyridine is a high-purity, multi-halogenated bipyridine derivative, serving as a critical and versatile building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used to construct complex heterocyclic cores for next-generation herbicides and fungicides.
• Ligand Precursor: Serves as a starting material for synthesizing specialized bipyridine-based ligands used in catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to its bromo and chloro substituents.
• Chemical Biology Probes: Utilized to create tagged molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-Bromo-2'-Chloro-[3,4']-Bipyridine
CAS No.	942206-01-1
Molecular Formula	C10H6BrClN2
Molecular Weight	269.53 g/mol
Synonyms	5-Bromo-2'-chloro-3,4'-bipyridine; 2'-Chloro-5-bromo-3,4'-bipyridine; 3,4'-Bipyridine, 5-bromo-2'-chloro-; 5-Bromo-2'-chloro-[3,4']bipyridyl; [3,4']Bipyridinyl, 5-bromo-2'-chloro-; 942206-01-1 (CAS); 5-Br-2'-Cl-3,4'-bipyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2'-Chloro-[3,4']-Bipyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our standard is to supply material with a typical purity of ≥97% (HPLC), meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.