Description

Pentafluorophenyl 2-Morpholin-4-Ylpyrimidine-5-Carboxylate is a high-purity, specialized chemical building block designed for advanced research and development. This compound is valued for its unique molecular structure, which incorporates both a pentafluorophenyl ester and a morpholinylpyrimidine core, making it a versatile intermediate in synthetic chemistry. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials research organizations for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Proteomics: Serves as a reactive handle or linker in activity-based protein profiling (ABPP) and the synthesis of chemical probes due to the reactive pentafluorophenyl ester group.
• Material Science: Employed in the creation of novel organic frameworks, polymers, or coatings where its specific fluorinated and heterocyclic properties can impart desired characteristics.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental studies in organic synthesis methodology and reaction discovery.

Basic Information

Product Name	Pentafluorophenyl 2-Morpholin-4-Ylpyrimidine-5-Carboxylate
CAS No.	941717-05-1
Molecular Formula	C16H11F5N3O3
Molecular Weight	388.27 g/mol
Synonyms	2-Morpholino-5-((perfluorophenoxy)carbonyl)pyrimidine; Pentafluorophenyl 2-(morpholin-4-yl)pyrimidine-5-carboxylate; 5-Carboxy-2-morpholin-4-ylpyrimidine pentafluorophenyl ester; 2-(4-Morpholinyl)-5-pyrimidinecarboxylic acid 2,3,4,5,6-pentafluorophenyl ester; 941717-05-1; PFP-2-Morpholinopyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 2-Morpholin-4-Ylpyrimidine-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.