Description

4-Isocyanato-4-Phenyltetrahydropyran CAS NO 941717-02-8 is a specialized isocyanate derivative featuring a tetrahydropyran ring, serving as a versatile and high-value building block in advanced organic synthesis. Its core value proposition lies in its unique structure, which enables the introduction of both isocyanate functionality and a rigid, oxygen-containing heterocycle into target molecules, facilitating the development of novel materials with tailored properties. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries who require precise molecular scaffolds for creating active ingredients, functional monomers, or advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the tetrahydropyran moiety's prevalence in bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where its structure can contribute to improved biological activity and environmental profile.
• Specialty Polymer & Resin Production: Serves as a functional monomer for producing polyurethanes, polyureas, and other polymers with enhanced chemical resistance, adhesion, or thermal properties.
• Cross-linking Agent: Employed in coatings, adhesives, and elastomer formulations to introduce urethane linkages, improving durability and performance.
• Chemical Research & Development: A valuable reagent for academic and industrial labs exploring new organic reactions, heterocyclic chemistry, and material science.
• Liquid Crystal & OLED Material Precursor: Potential use in the synthesis of advanced electronic materials requiring specific molecular geometry and functional groups.

Basic Information

Product Name	4-Isocyanato-4-Phenyltetrahydropyran
CAS No.	941717-02-8
Molecular Formula	C12H13NO2
Molecular Weight	203.24 g/mol
Synonyms	4-Phenyl-4-isocyanatotetrahydropyran; 4-Isocyanato-4-phenyltetrahydropyran; 4-Phenyltetrahydropyran-4-yl isocyanate; Tetrahydropyran-4-yl(phenyl)methane isocyanate; 4-Phenyl-4-isocyanatooxane; 4-Phenyltetrahydro-2H-pyran-4-yl isocyanate; Isocyanic acid, 4-phenyltetrahydro-2H-pyran-4-yl ester
EINECS	Contact for details

Quality Control

Our 4-Isocyanato-4-Phenyltetrahydropyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to maximize shelf life and stability. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Impurities (HPLC)	Individual ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.