Description

Pentafluorophenyl 2-Morpholin-4-Yl-1,3-Thiazole-5-Carboxylate is a high-value, specialized organic building block featuring a reactive pentafluorophenyl ester group. This compound is critically important for its role as a versatile intermediate in advanced pharmaceutical and agrochemical research, enabling efficient coupling reactions under mild conditions. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Bioconjugation & Probe Synthesis: The reactive ester facilitates the labeling of biomolecules (peptides, proteins) for diagnostic and research applications.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique properties.
• Chemical Biology: Employed in activity-based protein profiling (ABPP) and the creation of covalent enzyme inhibitors.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Item	Details
Product Name	Pentafluorophenyl 2-Morpholin-4-Yl-1,3-Thiazole-5-Carboxylate
CAS No.	941716-88-7
Molecular Formula	C15H11F5N2O3S
Molecular Weight	394.32 g/mol
Synonyms	2-Morpholino-1,3-thiazole-5-carboxylic acid pentafluorophenyl ester; 5-Carboxy-2-morpholinothiazole pentafluorophenyl ester; Pentafluorophenyl 2-morpholinothiazole-5-carboxylate; 2-(Morpholin-4-yl)-1,3-thiazole-5-carboxylic acid 2,3,4,5,6-pentafluorophenyl ester; PFP-2-Morpholinothiazole-5-carboxylate; 941716-88-7; 4-Morpholin-2-yl-1,3-thiazole-5-carboxylic acid pentafluorophenyl ester
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 2-Morpholin-4-Yl-1,3-Thiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.