Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]- is a high-purity, advanced pharmaceutical intermediate featuring a brominated azaindole core protected by a SEM (2-(trimethylsilyl)ethoxymethyl) group. This compound matters as a critical building block for medicinal chemists, enabling precise synthetic modifications for drug discovery and development. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and biotechnology sectors for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products.
• Chemical Biology: Serves as a versatile scaffold for constructing molecular probes and tool compounds in biological studies.
• Material Science: Potential precursor for organic electronic materials due to its fused heterocyclic structure.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Utilized in university and institutional labs for methodological development and novel compound library generation.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Bromo-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]-
CAS No.	941685-08-1
Molecular Formula	C13H19BrN2OSi
Molecular Weight	327.29 g/mol
Synonyms	4-Bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-1-SEM-7-azaindole; 4-Bromo-1-((2-(trimethylsilyl)ethoxy)methyl)-7-azaindole; 4-Bromo-1-SEM-1H-pyrrolo[2,3-b]pyridine; 4-Br-1-SEM-7-azaindole; 1-((2-(Trimethylsilyl)ethoxy)methyl)-4-bromo-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-1-[[2-(trimethylsilyl)ethoxy]methyl]-7-azaindole; 941685-08-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized by advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and residual solvents are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is light-sensitive (store away from light). Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Individual impurity ≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.