Description

5-(Benzyloxy)-3-Bromopyridin-2-Amine is a high-purity brominated pyridine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the construction of complex molecular architectures with precision. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the preparation of advanced pesticides and herbicides, leveraging the reactivity of the bromine and amine functional groups.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its pyridine core.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(Benzyloxy)-3-Bromopyridin-2-Amine
CAS No.	941596-78-7
Molecular Formula	C₁₂H₁₁BrN₂O
Molecular Weight	279.13 g/mol
Synonyms	3-Bromo-5-(benzyloxy)pyridin-2-amine; 2-Amino-3-bromo-5-benzyloxypyridine; 5-Benzyloxy-3-bromopyridin-2-amine; 3-Bromo-5-(phenylmethoxy)-2-pyridinamine; 2-Pyridinamine, 3-bromo-5-(phenylmethoxy)-; 941596-78-7; 5-(Benzyloxy)-3-bromo-2-pyridinamine
EINECS	Contact for details

Quality Control

Our 5-(Benzyloxy)-3-Bromopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.