Description

T-Butyl 6-Bromo-3-Pyridinecarboxylate is a high-purity, versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive halogen handle and a protected carboxylic acid group, enabling efficient construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a starting material for creating novel pyridine-based ligands used in catalytic processes.
• Material Science Research: Building block for synthesizing functionalized polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Custom Synthesis and R&D: Employed in contract research and custom synthesis for exploring new chemical entities and process optimization.

Basic Information

Product Name	T-Butyl 6-Bromo-3-Pyridinecarboxylate
CAS No.	941294-58-2
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	6-Bromo-3-pyridinecarboxylic acid tert-butyl ester; tert-Butyl 6-bromonicotinate; 6-Bromonicotinic acid tert-butyl ester; 3-Pyridinecarboxylic acid, 6-bromo-, 1,1-dimethylethyl ester; 6-Bromo-3-(tert-butoxycarbonyl)pyridine; T-Butyl 6-bromonicotinate; 6-Bromopyridine-3-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our T-Butyl 6-Bromo-3-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, from early-stage R&D to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.