Description

3-n-Boc-Amino-4-Iodo-6-Phenylpyridine is a high-purity, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is critical for medicinal chemistry and pharmaceutical research, serving as a key intermediate in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile iodo and protected amine functional groups.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Buchwald-Hartwig aminations.
• Chemical Library Synthesis: Employed in the parallel and combinatorial synthesis of diverse compound libraries for high-throughput screening.
• Agrochemical Development: Serves as an intermediate in the research and development of new crop protection agents and pesticides.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysts or functional materials.

Basic Information

Product Name	3-n-Boc-Amino-4-Iodo-6-Phenylpyridine
CAS No.	941271-13-2
Molecular Formula	C16H17IN2O2
Molecular Weight	396.23 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-4-iodo-6-phenylpyridine; tert-Butyl (4-iodo-6-phenylpyridin-3-yl)carbamate; 3-Boc-amino-4-iodo-6-phenylpyridine; 4-Iodo-6-phenyl-3-pyridinamine, N-BOC-protected; Boc-3-amino-4-iodo-6-phenylpyridine; 941271-13-2; 3-N-Boc-amino-4-iodo-6-phenylpyridine
EINECS	Contact for details

Quality Control

Our 3-n-Boc-Amino-4-Iodo-6-Phenylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.