Description

tert-Butyl 2-Cyano-2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetate is a high-value, multifunctional chemical intermediate designed for advanced synthetic chemistry. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile pyridine core with a reactive cyanoacetate ester group. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the 5-(trifluoromethyl)pyridine moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in catalysis and material science applications.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic compounds and reaction methodologies.
• Fluorinated Compound Libraries: An essential component for generating diverse compound libraries in medicinal chemistry for high-throughput screening.

Basic Information

Product Name	tert-Butyl 2-Cyano-2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetate
CAS No.	941133-76-2
Molecular Formula	C13H13F3N2O2
Molecular Weight	286.25 g/mol
Synonyms	2-(5-(Trifluoromethyl)pyridin-2-yl)-2-cyanoacetic acid tert-butyl ester; tert-Butyl (5-(trifluoromethyl)pyridin-2-yl)(cyano)acetate; 2-Cyano-2-[5-(trifluoromethyl)-2-pyridinyl]acetic Acid 1,1-Dimethylethyl Ester; 2-(5-(Trifluoromethyl)pyridin-2-yl)-2-cyanoacetate tert-butyl ester; t-Butyl 2-cyano-2-(5-trifluoromethylpyridin-2-yl)acetate; Acetic acid, 2-cyano-2-[5-(trifluoromethyl)-2-pyridinyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Cyano-2-(5-(Trifluoromethyl)Pyridin-2-Yl)Acetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards where required for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.