Description

2-(Methylthio)Pyrimidine-5-Boronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern cross-coupling reactions in pharmaceutical and agrochemical research. Its core value lies in enabling the efficient synthesis of complex heterocyclic compounds, which are pivotal in developing new active ingredients. This advanced intermediate is primarily needed by R&D chemists and process development scientists in the life sciences sector, particularly for creating novel drug candidates and crop protection agents. CAS No. 940284-18-4.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing carbon-carbon bonds between pyrimidine derivatives and various aryl/heteroaryl halides.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) for potential therapeutics targeting various diseases.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Employed in the creation of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Development: Useful for creating molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Product Name	2-(Methylthio)Pyrimidine-5-Boronic Acid Pinacol Ester
CAS No.	940284-18-4
Molecular Formula	C12H19BN2O2S
Molecular Weight	266.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(methylthio)pyrimidine; 2-Methylsulfanylpyrimidine-5-boronic acid pinacol ester; 2-(Methylthio)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-(Methylmercapto)pyrimidine-5-boronic acid pinacol ester; 2-(Methylsulfanyl)pyrimidin-5-ylboronic acid pinacol ester; Pinacol 2-(Methylthio)pyrimidine-5-boronate
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)Pyrimidine-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including NMR and HPLC, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.