Description

3'-Cyano-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid is a high-purity, advanced pharmaceutical intermediate with the molecular formula C12H13N3O2 and a molecular weight of 231.25. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used as a versatile scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its bipyridinyl core.
• Agrochemical Development: Serves as a building block for creating new crop protection agents and herbicides.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value specialty chemicals.

Basic Information

Product Name	3'-Cyano-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid
CAS No.	939986-70-6
Molecular Formula	C12H13N3O2
Molecular Weight	231.25 g/mol
Synonyms	4-(2-Cyanopyridin-3-yl)piperidine-4-carboxylic acid; 3-(4-Carboxypiperidin-4-yl)picolinonitrile; 4-Carboxy-4-(2-cyano-3-pyridyl)piperidine; 3-(4-Carboxy-4-piperidinyl)-2-pyridinecarbonitrile; 2H-[1,2']Bipyridinyl-4-carboxylic acid, 3'-cyano-3,4,5,6-tetrahydro-; 939986-70-6
EINECS	Contact for details

Quality Control

Our 3'-Cyano-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the specified 98+% purity and is free from critical impurities. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and residual solvent levels is provided with each shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled in a controlled environment. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.