Description

3-[[(4-Chloro-2-Pyrimidinyl)Oxy]Methyl]-1-Piperidinecarboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Protease Inhibitor Synthesis: Serves as a key component in the development of protease inhibitor candidates for various therapeutic areas.
• Kinase Inhibitor Development: Employed in the construction of kinase inhibitor libraries and targeted molecules for oncology and inflammatory diseases.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects under cGMP or research-grade conditions.
• Chemical Biology: Acts as a probe or a tagged molecule in biochemical assays to study enzyme function and cellular mechanisms.

Basic Information

Product Name	3-[[(4-Chloro-2-Pyrimidinyl)Oxy]Methyl]-1-Piperidinecarboxylic Acid tert-Butyl Ester
CAS No.	939986-48-8
Molecular Formula	C15H20ClN3O3
Molecular Weight	325.79 g/mol
Synonyms	1-Boc-3-((4-chloropyrimidin-2-yloxy)methyl)piperidine; tert-Butyl 3-(((4-chloropyrimidin-2-yl)oxy)methyl)piperidine-1-carboxylate; 1-Piperidinecarboxylic acid, 3-[[(4-chloro-2-pyrimidinyl)oxy]methyl]-, 1,1-dimethylethyl ester; 3-((4-Chloro-pyrimidin-2-yloxy)-methyl)-piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-((4-chloro-2-pyrimidinyloxy)methyl)piperidine; 3-[(4-Chloro-2-pyrimidinyloxy)methyl]-1-piperidinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-[[(4-Chloro-2-Pyrimidinyl)Oxy]Methyl]-1-Piperidinecarboxylic Acid tert-Butyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. Comprehensive Certificates of Analysis (COA) with full analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.