Description

4-(4-Methyl-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) piperidine derivative with a molecular weight of 291.39, serving as a critical pharmaceutical intermediate and building block in advanced organic synthesis. Its value lies in its functionalized structure, which is essential for constructing complex molecules in medicinal chemistry and drug discovery programs. This compound is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides requiring specific piperidine-based scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic and Industrial R&D: Utilized in universities and corporate research centers for exploratory chemistry and process development.

Basic Information

Product Name	4-(4-Methyl-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-29-5
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	tert-Butyl 4-[(4-methylpyridin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(4-methyl-2-pyridinyl)amino]piperidine; 4-(4-Methyl-2-pyridinylamino)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[(4-methylpyridin-2-yl)amino]piperidine; N-(1-Boc-4-piperidinyl)-4-methyl-2-pyridinamine; 939986-29-5; Boc-4-(4-methyl-2-pyridinylamino)piperidine
EINECS	Contact for details

Quality Control

Our 98+% purity grade is manufactured under cGMP-compliant conditions where applicable, ensuring batch-to-batch consistency for critical R&D and scale-up processes. All products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with stringent industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this light-sensitive compound from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.