Description

4-(4-Methyl-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C15H23N3O2 and a molecular weight of 277.36. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile piperazine-pyridine scaffold for medicinal chemistry research and process development. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality building blocks for novel drug discovery and scale-up.

Application

This specialized intermediate serves as a key precursor in various synthetic pathways. Its primary and related applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperazine and pyridine moieties.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development and optimization of commercial-scale API manufacturing processes.
• Agrochemical Synthesis: Intermediate in the research and production of novel pesticides and herbicides.
• Ligand & Catalyst Development: Potential precursor for creating novel ligands used in catalytic systems or metal-organic frameworks (MOFs).
• Academic & Institutional Research: Employed in university and institutional labs for synthetic organic chemistry and heterocyclic compound studies.

Basic Information

Product Name	4-(4-Methyl-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-26-2
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	tert-Butyl 4-(4-methylpyridin-2-yl)piperazine-1-carboxylate; 1-Boc-4-(4-methyl-2-pyridyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(4-methyl-2-pyridinyl)piperazine; 4-(4-Methyl-2-pyridinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Boc-4-(4-methylpyridin-2-yl)piperazine; N-Boc-4-(4-methyl-2-pyridyl)piperazine; 939986-26-2; 2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-4-methylpyridine
EINECS	Contact for details

Quality Control

Our 4-(4-Methyl-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a purity of 98+% and conformity to the highest industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.