Description

4-[(3-Cyano-Pyridin-2-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular weight of 316.40. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitor libraries for drug discovery.
• Kinase Inhibitor Development: Employed in the construction of heterocyclic cores common to many kinase inhibitor scaffolds.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.
• Chemical Biology Probes: Can be utilized to create labeled compounds or probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	4-[(3-Cyano-Pyridin-2-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-22-8
Molecular Formula	C17H24N4O2
Molecular Weight	316.40 g/mol
Synonyms	tert-Butyl 4-[[(2-amino-3-pyridinyl)amino]methyl]-1-piperidinecarboxylate; 4-[(3-Cyano-2-pyridinylamino)methyl]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-Boc-4-[(3-cyano-2-pyridinylamino)methyl]piperidine; 1-(tert-Butoxycarbonyl)-4-[(3-cyano-2-pyridinylamino)methyl]piperidine; 4-[(3-Cyano-pyridin-2-ylamino)-methyl]-piperidine-1-carboxylic acid tert-butyl ester; 939986-22-8; tert-Butyl 4-(((3-cyanopyridin-2-yl)amino)methyl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 4-[(3-Cyano-Pyridin-2-Ylamino)-Methyl]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure a purity of 98+% and conformity to specification. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.