Description

3-(3-Cyano-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) pharmaceutical intermediate with the molecular formula C16H22N4O2 and a molecular weight of 302.37. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex nitrogen-containing heterocycles essential for drug discovery. It is primarily sought by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile building block for constructing complex piperidine and pyridine-based molecular scaffolds in lead optimization and structure-activity relationship (SAR) studies.
• Protease Inhibitor Synthesis: Serves as a core structural component in the synthesis of potential protease inhibitors for therapeutic applications.
• Kinase Inhibitor Development: Employed in the creation of novel kinase inhibitor libraries for high-throughput screening in oncology and inflammatory disease research.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	3-(3-Cyano-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-20-6
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	tert-Butyl 3-[(3-cyanopyridin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-3-[(3-cyano-2-pyridinyl)amino]piperidine; 1-(tert-Butoxycarbonyl)-3-[(3-cyano-2-pyridinyl)amino]piperidine; 3-[(3-Cyanopyridin-2-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; 2-[(1-Boc-3-piperidinyl)amino]-3-pyridinecarbonitrile; 939986-20-6; BOC-3-(3-Cyano-2-pyridinylamino)piperidine
EINECS	Contact for details

Quality Control

Our 3-(3-Cyano-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to relevant quality management systems, and material can be supplied under research-grade or cGMP standards to suit project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.