Description

4-(3-Cyano-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity (98+%) pharmaceutical intermediate with the molecular formula C16H22N4O2 and a molecular weight of 302.37. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and oncology.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Protease Inhibitor Scaffold: Serves as a core structural component in the design and synthesis of protease inhibitor libraries.
• Kinase Inhibitor Development: Employed as a building block for creating novel kinase inhibitors, a major class of targeted cancer therapies.
• Chemical Biology Probes: Utilized in the synthesis of specialized molecules for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under GMP or non-GMP conditions.

Basic Information

Product Name	4-(3-Cyano-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-19-3
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	tert-Butyl 4-[(3-cyanopyridin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(2-cyano-3-pyridinyl)amino]piperidine; 4-[(3-Cyanopyridin-2-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-[(3-cyanopyridin-2-yl)amino]piperidine; 939986-19-3; Boc-4-(3-cyano-2-pyridinylamino)piperidine
EINECS	Contact for details

Quality Control

Our 4-(3-Cyano-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.