Description

4-(3-Nitro-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C15H22N4O4 and a molecular weight of 322.36. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a versatile precursor for introducing the 4-(3-Nitro-Pyridin-2-Ylamino)-Piperidine moiety into more complex molecular architectures.
• API Manufacturing: Employed in the scaled-up production of active pharmaceutical ingredients under controlled GMP environments.
• Biochemical Research: Used as a tool compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.

Basic Information

Product Name	4-(3-Nitro-Pyridin-2-Ylamino)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-15-9
Molecular Formula	C15H22N4O4
Molecular Weight	322.36 g/mol
Synonyms	tert-Butyl 4-[(3-nitropyridin-2-yl)amino]piperidine-1-carboxylate; 1-Boc-4-[(3-nitro-2-pyridinyl)amino]piperidine; 4-[(3-Nitro-2-pyridinyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[(3-nitropyridin-2-yl)amino]piperidine; 4-(3-Nitro-pyridin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester; BOC-4-(3-Nitro-2-pyridinylamino)piperidine
EINECS	Contact for details

Quality Control

Our 98+% purity grade of this intermediate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.