Description

3-(5-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate (API intermediate) with a molecular formula of C16H24N2O3 and a molecular weight of 292.38. This compound is a critical building block in modern organic synthesis, valued for its role in constructing complex nitrogen-containing heterocycles essential for bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing and screening compound libraries targeting various biological pathways.
• Process Development & Scale-Up: Serves as a critical raw material for optimizing synthetic routes from laboratory to pilot and commercial scale production.
• Ligand and Catalyst Precursor: Potential utility in the preparation of specialized ligands for catalysis or metal-organic frameworks.
• Agrochemical Synthesis: Intermediate in the research and development of new crop protection agents and pesticides.

Basic Information

Product Name	3-(5-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-13-7
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	1-Boc-3-((5-methylpyridin-2-yl)oxy)piperidine; tert-Butyl 3-[(5-methyl-2-pyridinyl)oxy]-1-piperidinecarboxylate; 3-((5-Methylpyridin-2-yl)oxy)piperidine-1-carboxylic acid tert-butyl ester; 1-Piperidinecarboxylic acid, 3-[(5-methyl-2-pyridinyl)oxy]-, 1,1-dimethylethyl ester; 3-(5-Methyl-2-pyridyloxy)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-3-(5-methylpyridin-2-yloxy)piperidine
EINECS	Contact for details

Quality Control

Our 98+% purity grade of this intermediate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.