Description

4-(5-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate with a molecular formula of C16H24N2O3 and a molecular weight of 292.38. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a protected piperidine scaffold essential for modern drug discovery. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors seeking reliable, high-quality building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• API Synthesis: Used in the research and development of Active Pharmaceutical Ingredients (APIs) that incorporate functionalized piperidine and pyridine motifs.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and herbicides.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.
• Academic Research: Used in university and institutional laboratories for methodological development and the study of heterocyclic chemistry.

Basic Information

Product Name	4-(5-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	939986-12-6
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	tert-Butyl 4-[(5-methylpyridin-2-yl)oxy]piperidine-1-carboxylate; 1-Boc-4-((5-methyl-2-pyridyl)oxy)piperidine; 4-[(5-Methyl-2-pyridinyl)oxy]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-((5-methylpyridin-2-yl)oxy)piperidine; 4-(5-Methyl-2-pyridyloxy)piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(5-methylpyridin-2-yloxy)piperidine; BOC-4-(5-Methyl-2-pyridyloxy)piperidine
EINECS	Contact for details

Quality Control

Our 4-(5-Methyl-Pyridin-2-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure a purity of 98+%. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. Our quality management system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.