Description

4-Aminomethyl-3-Chloro-Benzoic Acid Methyl Ester Hydrobromide is a high-purity, pharmaceutically relevant organic salt used as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging its halogenated and functionalized benzoate structure.
• Peptide Mimetics & Conjugation: The aminomethyl group serves as a handle for conjugation or for constructing peptide-like structures in medicinal chemistry.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic & Industrial Research: A valuable reagent for methodological development and exploring new chemical reactions in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Aminomethyl-3-Chloro-Benzoic Acid Methyl Ester Hydrobromide
CAS No.	939980-25-3
Molecular Formula	C10H11BrClNO2
Molecular Weight	292.56 g/mol
Synonyms	Methyl 4-(aminomethyl)-3-chlorobenzoate hydrobromide; 3-Chloro-4-(aminomethyl)benzoic acid methyl ester hydrobromide; Benzoic acid, 4-(aminomethyl)-3-chloro-, methyl ester, hydrobromide; Methyl 3-chloro-4-(aminomethyl)benzoate HBr; 4-(Aminomethyl)-3-chlorobenzoic acid methyl ester hydrobromide
EINECS	Contact for details

Quality Control

Our 4-Aminomethyl-3-Chloro-Benzoic Acid Methyl Ester Hydrobromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.