Description

2-Bromo-6-(n-Boc-Piperidin-4-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine core and a Boc-protected piperidine moiety. This compound matters as a versatile and critical building block for medicinal chemists, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research and development teams in the pharmaceutical and biotechnology industries for drug discovery programs, particularly in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Drug Discovery Scaffold: Used as a core structure for constructing compound libraries in high-throughput screening for new therapeutic targets.
• Kinase Inhibitor Development: The bromopyridine and piperidine structure makes it valuable for creating potential inhibitors of various protein kinases.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Chemical Biology Probes: Serves as a starting material for synthesizing molecular probes used to study biological pathways and mechanisms.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects on behalf of pharmaceutical clients.

Basic Information

Item	Detail
Product Name	2-Bromo-6-(n-Boc-Piperidin-4-Yl)Pyridine
CAS No.	939960-51-7
Molecular Formula	C15H21BrN2O2
Molecular Weight	341.25 g/mol
Synonyms	tert-Butyl 4-(6-bromopyridin-2-yl)piperidine-1-carboxylate; 1-Boc-4-(6-bromo-2-pyridyl)piperidine; 2-Bromo-6-(1-Boc-4-piperidyl)pyridine; 6-Bromo-2-(1-Boc-4-piperidinyl)pyridine; 4-(6-Bromo-2-pyridinyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(6-bromopyridin-2-yl)piperidine; 939960-51-7; Boc-4-(6-Bromo-2-pyridyl)piperidine
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(n-Boc-Piperidin-4-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.