Description

Cyclobutyl-(6-Trifluoromethyl-Pyridin-2-Yl)-Amine CAS NO 939809-66-2 is a specialized heterocyclic amine building block featuring a cyclobutyl and a trifluoromethylpyridine moiety. This compound is valued for its unique structural properties, which are critical for modulating the biological activity and physicochemical characteristics of advanced molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can enhance lipophilicity and metabolic stability.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and protein-ligand interactions in biochemical assays.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	Cyclobutyl-(6-Trifluoromethyl-Pyridin-2-Yl)-Amine
CAS No.	939809-66-2
Molecular Formula	C10H11F3N2
Molecular Weight	216.20 g/mol
Synonyms	N-Cyclobutyl-6-(trifluoromethyl)pyridin-2-amine; 2-Cyclobutylamino-6-trifluoromethylpyridine; 6-(Trifluoromethyl)-2-pyridinyl-cyclobutylamine; Cyclobutyl-[6-(trifluoromethyl)pyridin-2-yl]amine; 2-Pyridinamine, N-cyclobutyl-6-(trifluoromethyl)-; Cyclobutylamine, N-(6-(trifluoromethyl)-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our Cyclobutyl-(6-Trifluoromethyl-Pyridin-2-Yl)-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.