Description

5-(Trifluoromethyl)Pyridin-2-Yl]Acetonitrile is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a nitrile and a trifluoromethyl group on a pyridine ring, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-(Trifluoromethyl)Pyridin-2-Yl]Acetonitrile
CAS No.	939793-18-7
Molecular Formula	C8H5F3N2
Molecular Weight	186.14 g/mol
Synonyms	2-(5-(Trifluoromethyl)pyridin-2-yl)acetonitrile; [5-(Trifluoromethyl)-2-pyridyl]acetonitrile; 2-Pyridineacetonitrile, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2-pyridineacetonitrile; (5-Trifluoromethyl-pyridin-2-yl)-acetonitrile; 939793-18-7; 5-(Trifluoromethyl)picolinonitrile (related structure)
EINECS	Contact for details

Quality Control

Every batch of 5-(Trifluoromethyl)Pyridin-2-Yl]Acetonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and we support customer audits and regulatory documentation as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.