Description

2-(1-Amino-2-tert-Butoxycarbonylamino-Ethyl)-Benzoic Acid Methyl Ester Dihydrochloride is a protected amino acid derivative, specifically a Boc-protected phenylalanine analog, that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined intermediates for the development of novel active pharmaceutical ingredients (APIs) and complex peptides. Its primary value lies in enabling precise molecular construction for the pharmaceutical, biotechnology, and agrochemical industries, where reliable supply and consistent quality are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for protease inhibitors and other targeted therapies.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid building block to introduce modified phenylalanine residues.
• Chemical Research & Development: Serves as a versatile starting material for medicinal chemistry programs, enabling the exploration of new chemical entities and structure-activity relationships (SAR).
• Agrochemical Synthesis: Employed in the development of advanced pesticides and herbicides that require specific chiral amino acid frameworks.
• Bioconjugation & Labeling: Useful in creating labeled compounds or conjugates for diagnostic and biochemical research applications.
• Academic Research: A valuable reagent for university and institutional labs studying synthetic methodology, asymmetric synthesis, and bioorganic chemistry.

Basic Information

Product Name	2-(1-Amino-2-tert-Butoxycarbonylamino-Ethyl)-Benzoic Acid Methyl Ester Dihydrochloride
CAS No.	939760-44-8
Molecular Formula	C16H25Cl2N2O4
Molecular Weight	380.29 g/mol
Synonyms	Methyl 2-(1-Amino-2-((tert-butoxycarbonyl)amino)ethyl)benzoate dihydrochloride; (R/S)-Methyl 2-(2-((tert-Butoxycarbonyl)amino)-1-aminoethyl)benzoate dihydrochloride; Boc-Phe(2-COOH-OMe)-OH·2HCl; 2-(2-(Boc-amino)-1-aminoethyl)benzoic acid methyl ester dihydrochloride; Methyl 2-(2-(tert-butoxycarbonylamino)-1-aminoethyl)benzoate dihydrochloride; N-Boc-2-amino-3-(2-(methoxycarbonyl)phenyl)propanoic acid amine salt dihydrochloride; A protected phenylalanine methyl ester derivative.
EINECS	Contact for details

Quality Control

Our 2-(1-Amino-2-tert-Butoxycarbonylamino-Ethyl)-Benzoic Acid Methyl Ester Dihydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.