Description

4,6-Difluoro-2-Pyridinamine is a fluorinated pyridine derivative, a versatile and high-value organic building block. Its core value lies in its unique difluoro-substituted pyridinamine structure, which is critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, serving as a key intermediate in the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the creation of complex molecular libraries for screening.
• Ligand Synthesis: Useful for constructing sophisticated ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	4,6-Difluoro-2-Pyridinamine
CAS No.	938443-45-9
Molecular Formula	C5H4F2N2
Molecular Weight	130.10 g/mol
Synonyms	2-Amino-4,6-difluoropyridine; 4,6-Difluoropyridin-2-amine; 4,6-Difluoro-2-aminopyridine; 2-Pyridinamine, 4,6-difluoro-; 4,6-Difluoro-2-pyridinylamine
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-2-Pyridinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.