Description

5-Chloro-4-(Chloromethyl)-3-Methyl-1-Phenyl-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Key synthetic intermediate for the research and development of novel pharmaceutical compounds.
• Building block in the synthesis of potential kinase inhibitors for oncology applications.
• Precursor in medicinal chemistry programs targeting CNS disorders.
• Used in process chemistry for scaling up API production under cGMP conditions.
• Valuable scaffold for generating compound libraries in high-throughput screening.
• Intermediate for the preparation of specialized fine chemicals and research reagents.

Basic Information

Product Name	5-Chloro-4-(Chloromethyl)-3-Methyl-1-Phenyl-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	938001-12-8
Molecular Formula	C15H11Cl2N3O
Molecular Weight	320.17 g/mol
Synonyms	5-Chloro-4-(chloromethyl)-3-methyl-1-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 938001-12-8; 1,7-Dihydro-5-chloro-4-(chloromethyl)-3-methyl-1-phenyl-6H-pyrazolo[3,4-b]pyridin-6-one; Pyrazolo[3,4-b]pyridin-6-one derivative; 4-(Chloromethyl)-5-chloro-3-methyl-1-phenyl-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-(Chloromethyl)-3-Methyl-1-Phenyl-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.