Description

Methyl 1-Isopropyl-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular scaffolds. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Methyl 1-Isopropyl-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate
CAS No.	938001-03-7
Molecular Formula	C14H19N3O2
Molecular Weight	261.32 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(1-methylethyl)-3,6-dimethyl-, methyl ester; Methyl 1-isopropyl-3,6-dimethylpyrazolo[3,4-b]pyridine-4-carboxylate; 1-Isopropyl-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid methyl ester; 938001-03-7; Pyrazolopyridine derivative; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylate ester
EINECS	Contact for details

Quality Control

Our Methyl 1-Isopropyl-3,6-Dimethyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.